My Research Papers
Scientific Research Studies
Birimberg-Schwartz L, Wilson DC, Kolho KL, Karolewska-Bochenek K, Afzal NA, Spray C, Romano C, Lionetti P, Hauer AC, Martinez-Vinson C, Veres G, Escher JC, Turner D; paediatric IBD Porto group of ESPGHAN. pANCA and ASCA in Children with IBD-Unclassified, Crohn's Colitis, and Ulcerative Colitis-A Longitudinal Report from the IBD Porto Group of ESPGHAN. Inflamm Bowel Dis. 2016 Apr 29. [Epub ahead of print]
Ashton JJ, Versteegh HP, Batra A, Afzal NA, King A, Griffiths DM, Beattie RM, Stanton MP. Colectomy in pediatric ulcerative colitis: A single center experience of indications, outcomes, and complications. J Pediatr Surg. 2016 Feb;51(2):277-81
Ashton JJ, Coelho T, Ennis S, Batra A, Afzal NA, Beattie RM. Endoscopic versus histologic disease extent at presentation of paediatric inflammatory bowel disease (PIBD). Journal of Pediatric Gastroenterology and Nutrition. 2016 Feb;62(2):246-51
Tomlin J, Slater H, Muganthan T, Beattie RM, Afzal NA. Parental knowledge of Coeliac disease. Inform Health Soc Care. 2015 Sep;40(3):240-53.
Andreoletti G, Ashton JJ, Coelho T, Willis C, Haggarty R, Gibson J, Holloway J, Batra A, Afzal NA, Beattie RM, Ennis S. Exome analysis of patients with concurrent pediatric inflammatory bowel disease and autoimmune disease. Inflamm Bowel Dis. 2015 Jun;21(6):1229-36.
Ashton JJ, Coelho T, Ennis S, Batra A, Afzal NA, Beattie RM. Presenting phenotype of paediatric inflammatory bowel disease in Wessex, Southern England 2010-2013. Acta Paediatr. 2015 Aug;104(8):831-7.
Rahman I, Afzal NA, Patel P. The role of magnetic assisted capsule endoscopy (MACE) to aid visualisation in the upper GI tract. Comput Biol Med. 2015 Mar 24
Ashton JJ, Wiskin AE, Ennis S, Batra A, Afzal NA, Beattie RM. Rising incidence of paediatric inflammatory bowel disease (PIBD) in Wessex, Southern England. Arch Dis Child. 2014 Jul;99(7):659-64.
Blackburn SC, Wiskin AE, Barnes C, Dick K, Afzal NA, Griffiths DM, Beattie RM, Stanton MP. Surgery for children with Crohn's disease: indications, complications and outcome. Arch Dis Child. 2014 May;99(5):420-6.
Venkataraman D, Howarth L, Beattie RM, Afzal NA. A very high Amylase can be benign in Crohn’s disease. BMJ Case Reports 2012 Jul 10;2012. pii: bcr0220125917. doi: 10.1136/bcr.02.2012.5917
Christodoulou K, Wiskin AE, Gibson J, Tapper W, Willis C, Afzal NA, Upstill-Goddard R, Holloway JW, Simpson MA, Beattie RM, Collins A, Ennis S. Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes. Gut. 2012 Apr 28 [online print]
Wiskin AE, Wootton SA, Cornelius VR, Afzal NA, Elia M, Beattie RM. No relationship between disease activity measured by clinical score, local and systemic inflammatory markers and resting energy expenditure in childhood Crohn’s disease. Journal of pediatric gastroenterology and nutrition. 2012 Feb;54(2):271-6.
Russell RK, Wilson ML, Loganathan S, Bourke B, Kiparissi F, Mahdi G, Torrente F, Rodrigues A, Davies I, Thomas A, Akobeng AK, Fagbemi A, Hyer W, Spray C, Vaish S, Rogers P, McGrogan P, Heuschkel RB, Aub N, Fell JM, Afzal NA, Green M, Murphy MS, Rao P, Shah N, Ho GT, Naik S, Wilson DC. A British society of paediatric gastroenterology, hepatology and nutrition survey of the effectiveness and safety of Adalimumab in children with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics 2011 April; 33(8):946-53. Epub 2011 Feb 22
Wiskin AE, Wootton SA, Hunt TM, Cornelius VR, Afzal NA, Jackson AA, Beattie RM. Body composition in childhood inflammatory bowel disease. Clinical Nutrition 2011 Feb; 30(1):112-5 Epub 2010 Aug 21
Afzal NA, Shenoy MU, Haque S, Wilcox DT, Shah N. Recognition and treatment of genitourinary complications in paediatric Crohn’s disease using Infliximab. Acta Paediatrica 2010 July;99(7):1042-6. Epub 2010 Feb 23
Erlewyn-Lajeunesse M, Walker W, Basarab A, Eren E, Afzal N, Godfrey K, Faust SN. Linezolid an oral treatment for Staphylococcal liver abscess in chronic granulmoatous disease. Paediatric Infectious Disease Journal 2009 Nov; 28(11):1036-7
Wiskin AE, Wootton SA, Culliford DJ, Afzal NA, Jackson AA, Beattie RM. Impact of disease activity on resting energy expenditure in children with inflammatory bowel disease. Clin Nutr. 2009 Jun
Tighe MP, Morenas RA, Afzal NA, Beattie RM. Erythema ab igne and Crohn's disease. Archives Diseases in Childhood. 2008 May;93(5):389
Morenas RA, Tighe MP, Moore I, Afzal NA, Beattie RM. Latent coeliac disease in childhood? Gut. 2008 May;57(5):715-6
Howarth LJ, Wiskin AE, Griffiths DM, Afzal NA, Beattie RM. Outcome of childhood ulcerative colitis at 2 years. Acta Paediatr. 2007 Dec;96(12):1790-3
Thomson M, Antao B, Hall S, Afzal N, Hurlstone P, Swain CP, Fritscher-Ravens A. Medium-term outcome of endoluminal gastroplication with the EndoCinch device in children. J Pediatr Gastroenterol Nutr. 2008 Feb;46(2):172-7
Afzal NA, Ozzard A, Keady S, Thomson M, Murch S, Heuschkel R. Infliximab delays, but does not avoid, the need for surgery in treatment-resistant paediatric Crohn’s disease. Digestive diseases and sciences 2005. Dig Dis Sci. 2007 Dec;52(12):3329-33
Afzal NA, Davies S, Paintin M, Arnaud-Battandier F, Walker-Smith JA, Murch SH, Heuschkel R, Fell JM. Colonic Crohn’s disease in children does not respond well to treatment with enteral nutrition if the ileum is not involved. Digestive diseases and sciences 2005; Aug;50(8):1471-5
Thomson M, Sharon H, Afzal N, Ashwood P, Fritscher-Ravens A, Swain P. Endoluminal gastroplication in children with gastro-oesophageal reflux disease: 1 year follow-up. Gut. Dec 2004;53(12):1745-50
Castellaneta SP, Afzal NA, Greenberg M, Francavilla R, Deere H, Davies S, Murch SH, Walker-Smith JA, Thomson M. Diagnostic role of upper gastrointestinal endoscopy in paediatric inflammatory bowel disease. Journal of pediatric gastroenterology and nutrition. Sep 2004;39(3):257-61
Afzal NA, Loonen H, Arnaud- Battandier F, Davies S, Murch S, Derkx B, Heuschkel R, Fell J. Improvement in quality of life in children with acute Crohn’s disease does not parallel mucosal healing after treatment with exclusive enteral nutrition. Alimentary Pharmacology and Therapeutics 2004 Jul 15;20(2):167-72
Afzal NA, Murch SH, Thirrupathy K, Berger L, Fagbemi A, Heuschkel RB. Constipation with acquired megarectum in children with autism. Pediatrics 2003 Oct;112(4):939-42
Dick A, Keady S, Mohamed F, Brayley S, Thomson M, Lloyd BW, Heuschkel R, Afzal NA. Use of unlicensed and off-label medications in paediatric gastroenterology with a review of the commonly used formularies in UK. Alimentary Pharmacology and Therapeutics 2003 Feb;17(4):571-5.
Afzal NA, Albert D, Lloyd-Thomas A, Thomson M. A child with oesophageal strictures. Lancet 2002 Mar 23;359(9311):1032
Afzal NA, Addai SA, Fagbemi A, Murch SH, Thomson MA, Heuschkel RB. Refeeding syndrome with enteral nutrition in children: a case report, literature review and clinical guidelines. Clinical Nutrition 2002 Dec;21(6):515-20.
Heuschkel R, Afzal N, Wuerth A, Tolia V, Kemper K, Bousvaros A. The use of alternative medicines in children and young adults with inflammatory bowel disease. American Journal of Gastroenterology 2002 Feb;97(2):382-8
Afzal NA, Brueton M, Fell JM, Baker A. Portal vein thrombosis and pancreatic failure. International Journal of Pancreatology 2001; 29 (2), 109-113
Afzal NA, Martin DI, Atkinson PI. Missing milestones. Early Child Development and Care 2001;167: 51-62
Rahman I, Patel P, Boger P, Rasheed S, Thomson M, Afzal NA. Therapeutic upper gastrointestinal tract endoscopy in Paediatric Gastroenterology. World J Gastrointest Endosc. 2015 Mar 16;7(3):169-82. doi: 10.4253/wjge.v7.i3.169. Review.
Tighe M, Afzal NA, Bevan A, Hayen A, Munro A, Beattie RM. Pharmacological treatment of children with gastro-oesophageal reflux. Cochrane Database Syst Rev. 2014 Nov 24;11:CD008550.
Tighe MP, JR Fraser Cummings, Afzal NA. Nutrition and inflammatory bowel disease: primary or adjuvant therapy. Current Opinion in Clinical Nutrition and Metabolic Care 2011 Sep; 14(5): 491-6
Afzal NA, Tighe MP, Thomson MA. Constipation in children. Italian Journal of Pediatrics 2011, June 13;37:28
Tighe MP, Afzal NA, Bevan A, Beattie RM. Current pharmacological management of gastro-esophageal reflux in children: an evidence-based systematic review. Paediatric Drugs. 2009;11(3):185-202
Afzal NA, Thomson M. Constipation in Children. Independent Nurse. Healthcare Republic News. September 2008.
Also available online
Afzal NA, Thomson M. Constipation in Children. GP. Healthcare Republic News. October 2007
Also available online
Beattie RM, Croft NM, Fell JM, Afzal NA, Heuschkel RB. Inflammatory bowel disease. Archives of diseases in childhood.
Afzal NA, Thomson M. Diarrhoea and gastroenteritis in the infant and young child. The journal of family health care 2002; 12 (6):146-150
Afzal NA, Thomson M. Management of constipation in children. Prescriber. May 19, 2001; 101-107
Afzal NA, Thomson M. Interventional Endoscopy: recent innovations. Pediatric Gastrointestinal Disease. Pathophysiology, diagnosis, management. 6th edition (in press).
Afzal NA, Thomson M. Interventional Endoscopy: recent innovations. Pediatric Gastrointestinal Disease. Pathophysiology, diagnosis, management. 5th edition.
Afzal NA, Heuschkel RB. Alternative Medical Treatment. Pediatric Gastrointestinal Disease. Pathophysiology, diagnosis, management. 4th edition.
Afzal NA, Thomson M. Diverticular disease in adolescence. Balliere’s best practice & research: Clinical gastroenterology; 16 (4): 621-34
Rahman I, Patel P, Boger P, Thomson M, Afzal NA. Utilisation of magnets to enhance gastrointestinal endoscopy. World Journal of Gastrointestinal Endoscopy 2015 Dec 25;7(19):1306-1
Ahmed F, Afzal NA. Editors. Medical Disaster Response Manual, 3rd edition (167 pages). Published by Humanity First International and Humanity First Medical.
This manual forms the basis for the Humanity First disaster response course which has been running for the last three years in the UK and more recently in the US. The last course in 2012 was supported by Department for International Development, UK (DFID) and facilitated by Humanity First; the manual approved for use in the course by DFID.
Afzal F, Afzal NA and Bullard C. Editors & Authors. Atoms for Peace. This ebook is an informative scientific work, intended for young scientists and lay readers, in which an in-depth analysis of the power and the effects of nuclear power is given. It is a book primarily addressed at the young, questioning mind; at people who are finding out about the great questions of our modern world.
Online Training modules for doctors
Tighe M, Martin J, Afzal NA. Guideline debrief: GORD in children. 2 hours CPD. Pulse Learning. (34 Reviews - Readership Rating of 4 out of 5 stars)